Maria of Castile

Maria of Castile (14 September 1401 – 4 September 1458) was Queen of Aragon and Naples as the spouse of Alfonso V of Aragon. Maria acted twice as the regent of Aragon during the reign of her spouse, as he was absent during most of his reign; those regencies lasted between 1420 and 1423 and between 1432 and 1458. She was also briefly Princess of Asturias in her own right as the heiress presumptive to the throne of Castile. She succeeded her father, Henry III of Castile, as Princess of Asturias in 1402.

Source: Wikipedia — https://en.wikipedia.org/wiki/Maria_of_Castile